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5 nM (mCCR2) in binding antagonism and 3
In an intracellular Ca2+ (iCa2+) mobilization assay using HT29 colon cancer cells
EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function
Grossfeld GD
4S)-4-hydroxyoxan-3-yl]-5-methyl-6-{[4-(1H-pyrazol-1-yl)phenyl]methyl}-2
Milademetan hioinosine 5 nM (mCCR2) in bindingMilademetan (DS 3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS 3032) induces G1 cell cycle arrest, senescence and apoptosis. Product information CAS Number: 1398568 47 2 Molecular Weight: 618. 53 Formula: C30H34Cl2FN5O4 Chemical Name: (3'R,4'S,5'R) N [(3R,6S) 6 carbamoyloxan 3 yl] 6'' chloro 4' (2 chloro 3 fluoropyridin 4 yl) 4,4 dimethyl 2'' oxo 1'',2''
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